Research Progress on Application of Ultrasonic Microbubbles in Treatment of Liver Cancer
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3971/j.issn.1000-8578.2022.22.0244
   		
        
        	
        		- VernacularTitle:超声微泡在肝癌治疗中的应用研究进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Jiaojiao YU
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Li ZHA
			        		
			        		;
		        		
		        		
		        		
			        		Shue ZENG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Ultrasonography, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430079, China
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Research Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Ultrasonic microbubble;
			        		
			        		
			        		
				        		Liver cancer;
			        		
			        		
			        		
				        		Targeted therapy
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Cancer Research on Prevention and Treatment
	            		
	            		 2022;49(10):1082-1085
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Ultrasound therapy and considerable progress in molecular imaging technologies have allowed the use of ultrasonic microbubbles not only in image enhancement but also in targeted drug or gene delivery as drug or gene carriers, respectively. Hence, ultrasound microbubbles carrying drugs or genes have become a novel type of tumor-targeting therapy technology. They do not emit radiation and are thus safe. Additionally, they are efficient and easy to reuse and facilitate drug or gene release. All these features offer attractive prospects for the treatment of liver cancer and provide novel treatment ideas for the disease. This article reviews the mechanism, applications, and existing problems of ultrasonic microbubbles in the treatment of liver cancer.