Research progress on the role of type II innate lymphoid cells in liver diseases.
10.3760/cma.j.cn501113-20220114-00021
- VernacularTitle:Ⅱ型固有淋巴细胞在肝脏疾病中的作用研究进展
- Author:
Ming Kai YU
1
;
Yue Jie ZHU
2
;
Jian Bing DING
1
;
Feng Bo ZHANG
3
;
Xiao Bo LU
4
Author Information
1. Department of Immunology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi 830011, China.
2. Reproductive Medicine Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
3. Department of Clinical Laboratory, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
4. Department of infection, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
- Publication Type:Journal Article
- Keywords:
Innate immunity;
Liver diseases;
Progress;
Type II innate lymphocytes
- MeSH:
Humans;
Immunity, Innate;
Lymphocytes;
Cell Differentiation;
Liver Diseases
- From:
Chinese Journal of Hepatology
2023;31(7):776-780
- CountryChina
- Language:Chinese
-
Abstract:
Type II innate lymphoid cell (ILC2) is a newly identified innate immunological cell that belongs to the lymphocyte lineage in cell morphology, resides in the body's mucosal tissues, and has the dual functions of innate and adaptive immunity to promote tissue remodeling and repair after injury. Additionally, it is involved in the occurrence and development of a variety of liver diseases and plays an important role in maintaining the immunological homeostasis of the liver region. This article reviews the differentiation, development, and biological functions of ILC2, with particular attention to the research progress in liver diseases.