Research progress and application prospect of stem cells in inflamed dental tissues on periodontal bone regeneration.
10.3760/cma.j.cn112144-20230302-00065
- VernacularTitle:炎症牙源性组织中的干细胞在牙周骨组织再生中的研究进展及应用前景
- Author:
Wei Jia WANG
1
;
Meng Meng LIU
1
;
Shao Hua GE
1
Author Information
1. Department of Periodontology, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan 250012, China.
- Publication Type:Journal Article
- From:
Chinese Journal of Stomatology
2023;58(7):694-698
- CountryChina
- Language:Chinese
-
Abstract:
Tissue engineering has become a research hotspot regarding periodontal bone regeneration in recent years. Generally, stem cells used in periodontal tissue engineering are derived from healthy dental tissues, while restricted due to the strict indication of tooth extraction and limited sources. Stem cells in inflamed dental tissues mainly derive from inflamed pulp, periapical and periodontal tissues. Stem cells in inflamed dental tissues are abundant and retain most of the basic characteristics of stem cell compared with the ones derived from healthy dental tissues, which can be a promising source of stem cells for periodontal bone regeneration. In this review, we summarize the current application and prospect of stem cells in inflamed dental tissues on periodontal bone regeneration, and then discuss their feasibility as seed cells, in order to provide a reference for future research and clinical application of stem cells in inflamed dental tissues.
