Mechanism of obesity affecting periodontal tissue regeneration and therapeutic strategies.
10.3760/cma.j.cn112144-20230318-00097
- VernacularTitle:肥胖影响牙周组织再生的机制及治疗策略
- Author:
Ri Xin CHEN
1
;
Li Chun ZHENG
1
;
Li Li LI
1
;
Yue LI
1
;
Fu Hua YAN
1
Author Information
1. Department of Periodontology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.
- Publication Type:Journal Article
- From:
Chinese Journal of Stomatology
2023;58(7):688-693
- CountryChina
- Language:Chinese
-
Abstract:
Obesity is an important health problem in our society today, which can lead to the chronic low-grade inflammation state, to be an inducement for many chronic diseases such as hypertension, type 2 diabetes and non-alcoholic fatty liver disease. As a common oral chronic infectious disease, periodontitis is mainly characterized by gingival inflammation, periodontal pocket formation, alveolar bone resorption and tooth mobility. The ultimate goal of periodontitis treatment is to achieve periodontal tissue regeneration in the defect area. As a major risk factor for periodontitis, obesity can alter the periodontal inflammatory microenvironment in multiple ways, affecting the effects of periodontal tissue regeneration ultimately. Therefore, this paper will review the relationship between obesity and periodontal tissue regeneration, mechanism of obesity affecting periodontal tissue regeneration and the therapeutic strategies of periodontal tissue regeneration, providing new ideas for periodontal tissue regeneration treatment in obesity.
