Research progress on prevention and local intervention of oral mucositis in patients with hematopoietic stem cell transplantation.
10.3760/cma.j.cn112144-20220819-00452
- VernacularTitle:造血干细胞移植患者口腔黏膜炎预防及局部干预的研究进展
- Author:
Xiao Yu ZHOU
1
;
Zheng Wen PAN
1
;
Jian Li ZHANG
1
;
Li Wei XU
1
;
Shu Yi DING
1
;
Ai Yun JIN
2
Author Information
1. Department of Bone Marrow Transplantation Center, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China.
2. Nursing Department, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China.
- Publication Type:Journal Article
- From:
Chinese Journal of Stomatology
2023;58(5):491-497
- CountryChina
- Language:Chinese
-
Abstract:
Oral mucositis (OM) is a common complication during hematopoietic stem cell transplantation. When OM occurs, with the destruction of oral mucosal barrier function, the formation of oral bacterial environment is accelerated, which has a negative impact on the life quality and clinical outcomes of patients. OM can be prevented by keeping the oral cavity clean, using the mouthwash properly, and limiting the delivery of cytotoxic drugs to oral tissues. This review describes the research progress on the prevention and local intervention of OM in patients with hematopoietic stem cell transplantation, in order to provide ideas for the selection of clinical intervention and management strategies on OM, and to provide references for exploring effective management methods for OM.