Determination of acid-resistant silicic particles in lung by micro-XRF and its application in diagnosis of drowning.
- Author:
Sun-lin HU
1
;
Jin-feng WEN
;
Wen-bin LAI
;
Chao FANG
;
Xiao-ting ZHANG
;
Song-cai WANG
;
Wei-lie DAI
;
Chao LIU
Author Information
1. Guangzhou Institute of Criminal Science and Technology, Guangzhou 510030, China. sunlin.hu@yahoo.com.cn
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Animals;
Drowning/diagnosis*;
Female;
Fluorescence;
Forensic Pathology/methods*;
Fresh Water/analysis*;
Lung/chemistry*;
Male;
Rabbits;
Silicon/analysis*;
Spectrometry, X-Ray Emission/methods*
- From:
Journal of Forensic Medicine
2010;26(4):257-259
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:Using microbeam X-ray fluorescence (Micro-XRF) analyzer for determination of acid-resistant silicic particles in lung, and to explore its potential application in diagnosis of drowning.
METHODS:Thirty two white rabbits were divided randomly into drowning group (n=12), post-mortem immersion group (n=10) and control group (n=10). Lungs and water sample were collected for determination of area concentration of acid-resistant silicic particles using Micro-XRF method.
RESULTS:The area concentration of acid-resistant silicic particles for the drowning water sample was 4.4 mm2/mL. For the lungs of drowning group, the post-mortem immersion group and the control group, the determined average values were (25.30 +/- 10.95) mm2/g, (1.68 +/- 0.63) mm2/g and (1.65 +/- 0.85) mm2/g, respectively, with a statistically significant difference between the drowning group and the other two groups.
CONCLUSION:The area concentration of acid-resistant silicic particles in lungs may be used as an indicator of drowning. The method is highly sensitive and rapid. It provides a potential application in drowning diagnosis.
