Micellar liquid chromatography and its application in toxicological analysis.
- Author:
Xiang-wei CHENG
1
,
2
;
Wen-hui JIANG
;
Jian-xin CHU
Author Information
1. Zhejiang Police College, Hangzhou 310053, China. xweicheng@
2. com
- Publication Type:Review
- MeSH:
Analgesics, Opioid/analysis*;
Barbiturates/chemistry*;
Benzodiazepines/chemistry*;
Chromatography, Liquid/methods*;
Humans;
Hypnotics and Sedatives/chemistry*;
Micelles;
Reproducibility of Results;
Sensitivity and Specificity;
Solvents/chemistry*;
Surface-Active Agents/chemistry*
- From:
Journal of Forensic Medicine
2010;26(1):56-63
- CountryChina
- Language:Chinese
-
Abstract:
Micellar liquid chromatography (MLC) is a reversed phase liquid chromatography with mobile phases containing surfactant above its critical micellar concentration (CMC). The basic mechanism and advantages of MLC in physicochemical analysis were reviewed, and its applications in analysis of drugs, barbiturates, benzodiazepines were chiefly introduced in this paper. MLC is a potential method to toxicological analysis due to strong selectivity, wide application scope and easy biological samples, etc.
