Concentration changes of amylase in vitreous humor of acute pancreatitis associated with different postmortem interval in rabbits.
- Author:
Xing-biao LI
1
;
Hai-yan ZHANG
;
Li-ming SHAO
Author Information
1. Department of Forensic Medicine, Wenzhou Medical College, Wenzhou 325027, China.
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Amylases/analysis*;
Animals;
Disease Models, Animal;
Female;
Male;
Pancreatitis/enzymology*;
Postmortem Changes;
Rabbits;
Spectrophotometry/methods*;
Taurocholic Acid;
Time Factors;
Vitreous Body/chemistry*
- From:
Journal of Forensic Medicine
2004;20(3):143-144
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate concentration changes of amylase in rabbits vitreous humor of acute pancreatitis associated with postmortem different interval.
METHODS:To induce animal model of acute pancreatitis with sodium taurocholate, observed concentration changes of amylase after different postmortem interval, then compared with normal.
RESULTS:The concentration of amylase in vitreous humor of rabbit 24h after death were related to postmortem interval significantly; The concluded formulae of the relationship between postmortem interval and amylase concentration is y=8.7420+0.7699x-0.0083x2 (R2=92.62792, F=14.89734, P=0.001).
CONCLUSION:Concentration changes of amylase in vitreous humor of acute pancreatitis associated with postmortem interval may provide a new sensitive and objective method for the forensic early injury time estimation.
