Research progress on liquid biopsy and its combination of radiology in diagnosis of pulmonary nodules
- VernacularTitle:液体活检生物标志物及其联合影像学在肺癌早期诊断中应用的研究进展
- Author:
Shuo SUN
1
,
2
;
Feng WANG
1
,
2
;
Li HE
1
,
2
;
Wenwen YANG
1
,
2
;
Biao HAN
1
,
2
;
Mengmeng ZHAO
3
;
Chang CHEN
1
,
3
,
4
;
Minjie MA
1
,
2
Author Information
1. The First Clinical Medical College of Lanzhou University, Lanzhou, 730000, P. R. China;
2. Department of Throcic Surgery, The First Hospital of Lanzhou University, Lanzhou, 730000, P. R. China
3. Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, 200433, P. R. China
4. Department of Throcic Surgery, The First Hospital of Lanzhou University, Lanzhou, 730000, P. R. China;
- Publication Type:Journal Article
- Keywords:
Liquid biopsy;
circulating tumor cells;
radiology;
radiomics;
pulmonary nodules;
review
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2023;30(02):313-319
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer is a malignant tumor with the highest mortality worldwide, and its early diagnosis and evaluation have a crucial impact on the comprehensive treatment of patients. Early preoperative diagnosis of lung cancer depends on a variety of imaging and tumor marker indicators, but it cannot be accurately assessed due to its high false positive rate. Liquid biopsy biomarkers can detect circulating tumor cells and DNA in peripheral blood by non-invasive methods and are gradually becoming a powerful diagnostic tool in the field of precision medicine for tumors. This article reviews the research progress of liquid biopsy biomarkers and their combination with clinical imaging features in the early diagnosis of lung cancer.
