Study on alkaloids of endophytic Trichoderma atroviride B7 from Colquhounia coccinea var. mollis
10.16438/j.0513-4870.2022-1104
- VernacularTitle:火把花内生真菌Trichoderma atroviride B7生物碱类成分研究
- Author:
Wen-yuan LI
1
;
Ying WANG
2
;
Ce KUANG
2
;
Kai GUO
3
;
Yan LIU
4
;
Sheng-hong LI
4
Author Information
1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China; Henan Engineering Research Center of Water Environment and Health, Zhengzhou University of Industrial Technology, Zhengzhou 451150, China
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China
3. State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
4. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China; State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
- Publication Type:Research Article
- Keywords:
italic>Colquhounia coccinea var.mollis;
endophytic fungus;
italic>Trichoderma atroviride;
atroviridanol;
alkaloids
- From:
Acta Pharmaceutica Sinica
2023;58(4):963-966
- CountryChina
- Language:Chinese
-
Abstract:
Nine compounds were isolated from the crude extract of the solid culture of endophyte Trichoderma atroviride B7 of Colquhounia coccinea var. mollis by silica gel column chromatography, Sephadex LH-20 gel column chromatography, and HPLC. They were identified as atroviridanol (1), 3-oxo-3-[(2-phenylethyl) amino]-propanoic acid (2), N-(2′-phenylethyl)-acetamide (3), neoechinulin A (4), echinulin (5), gancidin W (6), N-isobutyl-3-methylbutanamide (7), 5-acetamido-1-pentanol (8), and N-2-methylpropyl-2-methylbutenamide (9) by NMR, HR-MS, and so on. Among them, compound 1 is a new compound, and compounds 2-9 are firstly isolated from Trichoderma spp.
