Isolation and identification of two new compounds from Semen Persicae
10.16438/j.0513-4870.2022-1306
- VernacularTitle:山桃仁中2个新化合物的分离与鉴定
- Author:
Kai-zhi LI
1
;
Shu-ping YANG
1
;
Bo-tao LU
1
;
Yue-tong ZHU
1
;
Shuang-jing LIU
1
;
Wei-sheng FENG
2
;
Yan-zhi WANG
2
Author Information
1. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China
2. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China; Co-construction of Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan and Education Ministry of P. R. China, Zhengzhou 450046, China
- Publication Type:Research Article
- Keywords:
Rosaceae;
Semen Persicae;
chemical composition;
flavone glycoside;
lignan glycoside
- From:
Acta Pharmaceutica Sinica
2023;58(5):1288-1292
- CountryChina
- Language:Chinese
-
Abstract:
Five compounds were isolated from the ethyl acetate fraction of Semen Persicae by using various chromatographic methods, including ODS, Sephadex LH-20, HPLC and semipreparative HPLC. Their structures were identified by 1D-NMR, 2D-NMR, HR-ESI-MS, UV, IR, circular dichroism (CD) and ECD calculation techniques: (2R,3R)-5,7,4′-trihydroxy-3′-methoxy-3-formylflavan-3-ol-5-O-β-D-glucopyranoside (1), (7R,8S)-dihydrodehydrodiconiferyl 6″-benzoyl alcohol-9-O-β-D-glucopyranoside (2), (7R,8S)-dihydrodehydrodiconiferyl alcohol-9-β-O-D-glucopyranosid (3), 2-methoxy-4-(2-propenyl)-phenyl-O-β-D-glucopyranoside (4), 2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]-propane-1,3-diol (5). Compound 1 and 2 are new compounds, and compounds 3-5 were obtained from Prunus davidiana (Carr.) Franch. for the first time.
