Two new terpene glycosides from the Alpiniae Oxyphyllae Fructus
10.16438/j.0513-4870.2022-1211
- VernacularTitle:益智仁中2个新的萜苷化合物
- Author:
Yue-tong ZHU
1
;
Hao CHEN
1
;
Xiao-ning LIU
1
;
Kai-zhi LI
1
;
Shuang-jing LIU
1
;
Wei-sheng FENG
2
;
Yong-xian CHENG
3
;
Yan-zhi WANG
2
Author Information
1. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China
2. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China; Co-construction of Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan & Education Ministry of P. R. China, Zhengzhou 450046, China
3. School of Pharmaceutical Sciences, Institute for Inheritance-Based Innovation of Chinese Medicine, Shenzhen University, Shenzhen 518060, China
- Publication Type:Research Article
- Keywords:
Alpiniae Oxyphyllae Fructus;
chemical composition;
terpeneglycoside;
labdane diterpenoid;
carvacrol;
acid hydrolysis
- From:
Acta Pharmaceutica Sinica
2023;58(5):1283-1287
- CountryChina
- Language:Chinese
-
Abstract:
Two undescribed terpene glycosides and two compounds were isolated from the n-butanol fraction of Alpiniae Oxyphyllae Fructus by using various chromatographic methods, including MCI Gel, Sephadex LH-20, ODS, silica gel and semi-preparative HPLC. The structures of the isolated compounds were identified by spectroscopy methods (1D, 2D NMR, UV, IR, MS, etc.), and the absolute configuration of the compound 1 was determined by ECD calculation and acid hydrolysis. Compounds 1 and 2 are new compound, and compounds 3 and 4 were isolated from Alpiniae Oxyphyllae Fructus for the first time.
