Diquafossol sodium combined with Qingrun Yangmu oral liquid for the treatment of dry eye after cataract operation
10.3980/j.issn.1672-5123.2023.8.21
- VernacularTitle:地夸磷索钠联合清润养目口服液治疗白内障术后干眼
- Author:
Wen-Xi ZHOU
1
;
Jing JANG
1
;
Bing LIN
1
Author Information
1. Department of Health Management, Hospital of Chengdu University of TCM, Chengdu 610075, Sichuan Province, China
- Publication Type:Journal Article
- Keywords:
diquafossol sodium eye drops;
Qingrun Yangmu oral liquid;
cataract;
dry eye;
ocular surface management
- From:
International Eye Science
2023;23(8):1352-1356
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the clinical efficacy of diquafosol sodium(DQS)eye drops combined with Qingrun Yangmu oral liquid in the treatment of dry eye after phacoemulsification and intraocular lens implantation.METHODS:A total of 57 patients(65 eyes)with dry eye after cataract surgery, who were admitted to the ophthalmology department of our hospital from September 2020 to January 2021, were selected as the research objects. They were divided into a control group(28 cases, 32 eyes, treated with 3% DQS eye drops)and an observation group(29 cases, 33 eyes, treated with 3% DQS eye drops combined with the Qingrun Yangmu oral liquid)based on a random number table method. Indicators, such as ocular surface disease index(OSDI), non-invasive tear film break-up time(NIBUT), Schirmer I test(SIt), corneal fluorescein sodium staining(CFS), and TCM symptom score, were compared and analyzed between the two groups 1d before, 1wk after(before treatment), and 1mo after(after treatment)surgery.RESULTS:The total effective rates of the observation group and the control group after treatment were 88% and 75%, respectively. The OSDI, NIBUT and SIt of the two groups after treatment showed significant improvement compared to those before treatment(P<0.05). The NIBUT, SIt, CFS, and TCM symptom scores of the observation group after treatment were better than those of the control group(P<0.05). No adverse reactions were observed in both groups.CONCLUSION:Combined use of DQS eye drops and the Qingrun Yangmu oral liquid can improve symptoms and clinical indicators of dry eye after cataract surgery, providing a new treatment method for ocular surface management of dry eye during the perioperative period of cataract surgery.
