Effect of panretinal photocoagulation combined with intravitreal Conbercept in the treatment of proliferative diabetic retinopathy with different stages
10.3980/j.issn.1672-5123.2023.8.02
- VernacularTitle:玻璃体腔注射康柏西普联合全视网膜激光光凝治疗不同分期增殖性糖尿病视网膜病变
- Author:
Tian-Hui SHAN
1
;
Jia-Xuan YU
1
;
Chun-Li LIU
1
;
Xiang GAO
1
;
Gong-Qiang YUAN
1
;
Xiao-Lei SUN
1
;
Jing-Jing ZHANG
1
Author Information
1. Eye Institute of Shandong First Medical University;Eye Hospital of Shandong First Medical University(Shandong Eye Hospital), Jinan 250021, Shandong Province, China; School of Ophthalmology, Shandong First Medical University, Jinan 250117, Shandong Province, China
- Publication Type:Journal Article
- Keywords:
proliferative diabetic retinopathy;
pars plana vitrectomy;
panretinal photocoagulation;
Conbercept
- From:
International Eye Science
2023;23(8):1242-1249
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effectiveness of panretinal photocoagulation(PRP)combined with intravitreal conbercept(IVC)for patients with different stages of proliferative diabetic retinopathy(PDR).METHODS: Retrospective study. The medical records for 100 patients(100 eyes)with PDR treated with PRP combined with IVC from January 2018 to June 2020 were reviewed, including 34 eyes with early PDR(group A), 43 with high-risk PDR(group B), and 23 with fibrovascular PDR(group C). The baseline information, best corrected visual acuity(BCVA), central macular thickness(CMT), the rate of vitrectomy and retinal detachment of the patients in the three groups at 1, 3, 6mo and the last follow-up after combination treatment were observed.RESULTS: The patients were followed up for 14.60±11.64mo(6-52mo), with a mean age of 54.22 ±9.32 years. We found 15 eyes(15.0%)who underwent vitrectomy after the combination treatment. The vitrectomy rates of the three groups were 2.9% in group A, 13.9% in group B, and 34.7% in group C. We found no instances of retinal detachment after the treatments. Most patients demonstrated improved BCVA and CMT values with the treatments.CONCLUSION: PRP combined with IVC is safe and effective in patients with different PDR stages.
