Clinical characteristics and treatment progress of microphthalmos-anophthalmos-coloboma
10.3980/j.issn.1672-5123.2023.7.15
- VernacularTitle:先天性小眼球-无眼球-眼组织缺损的临床特征及治疗进展
- Author:
Bo-Zhao WANG
1
;
Yan CUI
1
Author Information
1. Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan 250012, Shandong Province, China
- Publication Type:Journal Article
- Keywords:
microphthalmos;
coloboma;
angle-closure glaucoma;
cataract;
uveal effusion
- From:
International Eye Science
2023;23(7):1139-1143
- CountryChina
- Language:Chinese
-
Abstract:
Microphthalmos-anophthalmos-coloboma(MAC)is structurally and clinically correlated congenital ocular malformation. Although MAC is relatively rare, they still become an important cause of blindness in children. At present, the etiology of MAC is not clear; a variety of genetic or environmental factors may cause MAC. Because of its special anatomical structure, MAC has complex clinical manifestations and multiple complications. The complications including cataract, angle-closure glaucoma, uveal effusion, retinal detachment, orbital cyst, which are often accompanied with increased risks for surgery and poor prognosis. By summarizing the clinical features, the common types of ocular complications, and the progress of the treatment, this article will enhance clinicians' cognition of MAC and guide clinicians to formulate personalized and safe treatment plans for patients.
