Common microbes detected by conjunctival swab analysis and their antibiotic sensitivety
- VernacularTitle:Нүдний арчдасын нян судлалын шинжилгээнд зонхилон илэрсэн нян ба тэдгээрийн антибиотикт мэдрэг чанарын судалгаа
- Author:
Tserendavaa P
1
;
Khishigsuren N
2
Author Information
1. Ikher Talst Eye Clinic
2. Gyals Medical Center
- Publication Type:Journal Article
- Keywords:
DiConjunctivitis;
conjunctival swab analysis;
antibiotic sensitivity
- From:Innovation
2021;14(1-Ophthalmology):18-21
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Bacterial ocular infection is a common problem.[1;6]. Microbiological investigation
of the conjunctival swab is one of the broadly used method to study etiological agent of
conjunctivitis[2]. Microbial culture techniques have shown that 80% of conjunctival swabs yield
cultivable microbes.[3]. Conjunctival sac contains variety of pathogenic and non-pathogenic
microbes. Normal microbes play a protective immunological role in preventing the proliferation
of pathogenic species that can cause ocular infections whereas pathogenic microbes contribute
to infectious and autoimmune diseases of the eye. [4;5]
Purpose:To investigate common microbes detected by conjunctival swab analysis and their
antibiotic sensitivity.
Methods:In our descriptive study, 264 conjunctival swab samples that had been analyzed by
MALDI-TOF technology using VITEX MS at Gyals Medical Center from July 2019 to November 2020
were evaluated.
Results:Cultivable microbes and fungus were detected in 71.56% of overall swabs. 28.44% were
non cultivable. Fungus and 43 different types of microbes were found. 35% of all microbes were
Staphylococcus including Methicillin -resistant Staphylococcus aureus, Staphylococcus aureus,
Staphylococcus epidermidis. 28% of microbes were Streptococcus including Streptococcus
mitis, Streptococcus pneumoniae, Streptococcus anginosus, Streptococcus parasanguinis,
Streptococcus agalactiae, Streptococcus pyogenes, Streptococcus salivarius, Streptococcus spp.
20% of all microbes were miscellaneous bacterium including Enterococcus, Corynebacterium,
Klebsiella, Acinetobacter, Escherichia, Candida parapsilosis and the remaining are others.
Staphylococcus aureus is sensitive to Quinupristin/Dalfopristin, Linezolid, Vancomycin, Tigecycline,
Nitrofurantoin whereas they are resistant to Benzylpenicillin, Ciprofloxacin, Amoxicillin, Amoxicillin/
Clavulanic Acid, Cefazolin that are widely used in Mongolia.
Conclusion:In 76.71% of overall conjunctival swab samples were found cultivable microbes.
Methicillin -resistant Staphylococcus aureus, Staphylococcus aureus, Staphylococcus epidermidis
are the most common microbes detected by conjunctival swab analysis. The common microbes
are resistant to Benzylpenicillin, Ciprofloxacin, Amoxicillin, Amoxicillin/Clavulanic Acid, whereas
they are sensitive to Quinupristin/Dalfopristin, Linezolid, Vancomycin, Tigecycline, Nitrofurantoin,
Erythromycin, Clindamycin.
- Full text:InnoOpht-2021-14(1);18-21.pdf
