Comparison and enlightenment of anti-infective medicines between WHO model list of essential medicines for children，essential medicine list of WHO and national essential medicine list
- VernacularTitle:WHO儿童基本药物示范目录、WHO和我国基本药物目录中抗感染药物的比较与启示
- Author:
Tu DONG
1
;
Xin MA
2
;
Shuli MA
3
;
Wei LIU
1
Author Information
1. College of Pharmacy，Zhengzhou University，Zhengzhou 450001，China
2. Henan Provincial Drug Evaluation and Inspection Center，Zhengzhou 450008，China
3. Dept. of Pharmacy，Children’s Hospital Affiliated to Zhengzhou University，Zhengzhou 450012，China
- Publication Type:Journal Article
- Keywords:
anti-infective medicines;
Essential Medicine List;
medicine use of children;
WHO
- From:
China Pharmacy
2023;34(11):1293-1297
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To provide suggestions and reference for enriching the selection of anti-infective medicines for children in China and promoting the establishment of the Essential Medicine List for Children in China. METHODS Descriptive analysis method was used to statistically compare the differences and similarities of anti-infective medicines included in the World Health Organization Model List of Essential Medicines for Children （EMLc）， World Health Organization Model List of Essential Medicines （EML） and National Essential Medicine List （NEML） in terms of drug category， variety， dosage form， specification， symbol mark， etc. RESULTS All anti-infective medicines of EMLc were covered by EML （85.3%）. NEML lacked the information of anti-infective medicines relatively， and contained few new categories； for example， the third-generation and above cephalosporins in EMLc were not included， and the drug dosage forms were also relatively limited （mainly tablets， capsules and injections）， but the specifications were relatively rich. CONCLUSIONS With reference to EMLc， the guidance on the use of essential medicines for children in China should be added from the aspects of age， body weight， combined medication， etc.， and the dosage forms suitable for children such as oral liquid preparations and scored tablets should be added to NEML； when updating the NEML the newer drugs suitable for children such as cefixime and dacatavir should be included. Finally， with reference to the continuity of EML and EMLc， the Essential Medicine List for Children in China should be established based on NEML to meet the drug needs of children and promote the safe use of drugs in children.
