Antioxidant and anti-inflammatory activities of four kinds of Huangshan chrysanthemum
10.12206/j.issn.2097-2024.202211024
- VernacularTitle:4种黄山菊花品种的抗氧化和抗炎活性研究
- Author:
Lin WANG
1
;
Yu FANG
2
;
Wenwu YU
2
;
Ze HONG
2
Author Information
1. Huangshan Product Quality Inspection Institute, Huangshan 245000, China.
2. Huangshan Photosynthetic Ecological Agriculture Development Co., Ltd, Huangshan 245211, China.
- Keywords:
antioxidation;
anti-inflammation;
chrysanthemum;
feet swelling
- From:
Journal of Pharmaceutical Practice
2023;41(5):325-328
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the antioxidant and anti-inflammatory activities of four kinds of Huangshan chrysanthemum. Methods ABTS, FRAP and DPPH were used to detect the antioxidant activities of Huangshan golden silk chrysanthemum, Huangshan chrysanthemum, Huangshan gongju, and Huangshan dendranthema. Their anti-inflammatory activities were evaluated by NF-κB reporter gene assay and rat foot swelling models. Results The outcomes of ABTS，FRAP and DPPH showed that the water extracts of four kinds of chrysanthemum all had certain antioxidant activities and the activities of Huangshan golden silk chrysanthemum were strongest, followed by Huangshan chrysanthemum , Huangshan gongju , and Huangshan dendranthema. Results of NF-κB reporter gene assay and rat foot swelling models showed that four extracts of chrysanthemum morifolium could inhibit the transcription of NF-κB induced by LPS and alleviate foot swelling of rat induced by carrageenan, with the strongest activity of Huangshan chrysanthemum, followed by Huangshan golden silk chrysanthemum, Huangshan gongju, and Huangshan dendranthema. Conclusion The antioxidant activities of Huangshan golden silk chrysanthemum were strongest, followed by Huangshan chrysanthemum, Huangshan gongju, and Huangshan dendranthema. The anti-inflammatory activities of Huangshan chrysanthemum were strongest, followed by Huangshan golden silk chrysanthemum, Huangshan gongju, and Huangshan dendranthema.
