Determination level of antibody against COVID-19 vaccination in workers of FSCH
- VernacularTitle:Улсын нэгдүгээр төв эмнэлгийн ажилчдад КОВИД-19-ийн вакцинжуулалтын дараа эсрэгбиеийн түвшин тодорхойлсон дүн
- Author:
Oyunbileg B
1
;
Urangoo B
1
;
Otgontsetseg B
1
;
Bolortsetseg J
1
;
Narmandakh G
1
;
Bolor Ch
2
;
Sarantsetseg J
1
Author Information
1. Department of Laboratory Medicine, FCHM
2. Public Health Service, FCHM
- Publication Type:Journal Article
- From:
Health Laboratory
2021;14(2):13-16
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction:Health care workers of First Central Hospital of Mongolia have vaccinated with three different vaccines against SARS-CoV-2. We detected SARS-CoV-2 N and S-RBD antibodies after 30-90 days of second dose of vaccination.
Method:Quantitation of antibodies to the spike protein of SARS-CoV-2 was performed for the detection of adaptive immune response in 291 HCWs vaccinated with Covishield, Sinopharm and Pfizer Biontech. Detection and quantitation of SARS-CoV-2 N and S antibodies were performed by the electrochemiluminesce assay Cobas e411, Roche.
Result:SARS-CoV-2-S-RBD IgG titer were negative 0%, weak positive 0.4%, positive 17.5%, strong positive 82.1% of 246 HCWs vaccinated with Covishield and were negative 2.8%, weak positive 8.5%, positive 57.1%, strong positive 31.4% of 35 HCWs vaccinated with Sinopharm.
In all HCWs vaccinated with Pfizer Biontech SARS-CoV-2-S-RBD IgG titers were strong positive.
Conclusion:Humoral immunity was produced in HCWs after two doses of Covishield vaccine 100%, Sinopharm 97.0%, Pfizer Biontech 100% respectively. Antibody titer was higher among younger age workers.
- Full text:HL-2021-14(2)-13-16.pdf
