Current research status of hepatitis D virus RNA detection
10.3969/j.issn.1001-5256.2023.04.004
- VernacularTitle:HDV RNA检测的研究现状
- Author:
Yao GAO
1
;
Feng REN
1
;
Zhongping DUAN
2
Author Information
1. Beijing Municipal Key Laboratory of Liver Failure and Artificial Liver Treatment Research, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China;Beijing Institute of Hepatology, Beijing 100069, China
2. Beijing Municipal Key Laboratory of Liver Failure and Artificial Liver Treatment Research, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China
- Publication Type:Discussions by Experts
- Keywords:
Hepatitis Delta Virus;
RNA;
Diagnosis
- From:
Journal of Clinical Hepatology
2023;39(4):758-765
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis D caused by hepatitis D virus (HDV) infection is the most serious type of viral hepatitis. The prevalence rate of HDV has been seriously underestimated due to the lack of accurate HDV RNA detection methods. HDV RNA is the gold standard for the diagnosis of HDV infection and is of great significance in the diagnosis, screening, and treatment guidance of HDV. However, the multiple genotypes and strong secondary structure of HDV have led to great difficulties in HDV RNA detection. This article reviews the advances in HDV RNA detection methods and elaborates on the development from qualitative to quantitative detection methods, in order to provide new ideas for understanding the significance of HDV RNA detection and promoting the research and development of new HDV RNA detection methods.
