A comparison of current guidelines for the management of intrahepatic cholangiocarcinoma worldwide.
10.3760/cma.j.cn112139-20221125-00495
- VernacularTitle:肝内胆管癌国际临床实践指南和共识的诊疗建议比较
- Author:
Yan Xi YU
1
;
Zhong Jun WU
1
;
Wei TANG
2
;
Rui LIAO
1
Author Information
1. Department of Hepatobiliary Surgery, the First Hospital of Chongqing Medical University, Chongqing 400016, China.
2. National Center for Global Health and Medicine, Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, the University of Tokyo Hospital, Tokyo 162-8655, Japan.
- Publication Type:Journal Article
- From:
Chinese Journal of Surgery
2023;61(4):297-304
- CountryChina
- Language:Chinese
-
Abstract:
Intrahepatic cholangiocarcinoma (ICC) is the second most common human liver malignancy and its incidence rate has been gradually increasing worldwide over the past decades. Surgical resection (R0 resection) is the preferred potentially curative treatment for ICC patients. However, due to its conceal clinical features and high invasiveness, most patients have lost the opportunity for surgical resection at the time of diagnosis. In recent years, with the rapid development of targeted therapy and immunotherapy, which is represented by immune checkpoint inhibitors, clinicians are expected to provide more effective treatment options for patients with mid-stage or advanced ICC. At present, there are still controversial opinions on different guidelines regarding preoperative biliary drainage, the extent of hepatectomy, the definition of R0 resection, the width of the resection margin, lymph node dissection, postoperative recurrence, adjuvant therapy, etc. In this review, 12 guidelines or expert consensus published worldwide from 2012 to 2022 (including 4 Chinese guidelines, 4 European guidelines, 2 American guidelines and 2 Japanese guidelines) were retrieved. Focusing on sorting and comparing the current views on clinical management of ICC in different guidelines, this review aims to provide reference information for ICC clinical management and decision-making.
