Research progress on the modulation mechanism of electroacupuncture for learning and memory impairment after ischemic stroke.
10.13703/j.0255-2930.20220304-k0003
- Author:
Nan-Nan ZHAO
1
;
Yan-Jie LI
2
;
He-Wei QIN
2
;
Hui-Min DING
1
;
Xiao-Qiong HUA
1
;
Bo-Chao ZHU
1
;
Yu-Pu WANG
1
Author Information
1. School of Rehabilitation Medicine, Henan University of TCM, Zhengzhou 450046, China.
2. School of Rehabilitation Medicine, Henan University of TCM, Zhengzhou 450046, China; Rehabilitation Department, Henan Provincial Hospital of TCM, Zhengzhou
- Publication Type:Journal Article
- Keywords:
electroacupuncture;
ischemic stroke;
learning and memory impairment;
signaling pathway
- MeSH:
Humans;
Electroacupuncture;
Ischemic Stroke;
Learning;
Signal Transduction/physiology*
- From:
Chinese Acupuncture & Moxibustion
2023;43(2):239-244
- CountryChina
- Language:Chinese
-
Abstract:
Electroacupuncture may play a role in treatment of learning and memory impairment after ischemic stroke by regulating phosphatidylinositol-3-kinase (PI3K)/protein kinase B (Akt) signaling pathway, cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA)/cAMP response element binding protein (CREB) signaling pathway, nerve growth factor (NGF)/tyrosine kinase-A (TrkA) signaling pathway, Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling pathway, Notch signaling pathway, erythropoietin-producing hepatocyte (Eph)/ephrin signaling pathway. The interactions among these pathways should be further explored in treatment of learning and memory impairment after ischemic stroke.
