Prevalence of gastric cancer and its correlation with Helicobacter pylori infection in Enshi Tujia and Miao Autonomous Prefecture in 2011-2020
10.3969/j.issn.1006-2483.2023.02.025
- VernacularTitle:2011—2020年恩施地区胃癌流行情况及与幽门螺杆菌菌株感染的相关性分析
- Author:
Lili XIANG
1
;
Shun ZHU
2
;
Wei LI
3
;
Lei LEI
1
Author Information
1. Gastroenterology Department , Enshi Tujia and Miao Autonomous Prefecture Central Hospital , Enshi , Hubei 445000 , China
2. Critical Care , Enshi Tujia and Miao Autonomous Prefecture Central Hospital , Enshi , Hubei 445000 , China
3. PathologyEnshi , Enshi Tujia and Miao Autonomous Prefecture Central Hospital ,Enshi , Hubei 445000 , China
- Publication Type:Journal Article
- Keywords:
Gastric cancer;
Helicobacter pylori;
Incidence of a disease;
Mortality rate
- From:
Journal of Public Health and Preventive Medicine
2023;34(2):113-117
- CountryChina
- Language:Chinese
-
Abstract:
Objective Based on the incidence and mortality of gastric cancer and the correlation with helicobacter pylori (Hp) infection in Enshi Tujia and Miao Autonomous Prefecture from 2011 to 2020, the prevalence trend of gastric cancer in this decade was analyzed, providing theoretical basis for the prevention and treatment of gastric cancer in Enshi Tujia and Miao Autonomous Prefecture. Methods According to the unified national examination and evaluation standards, 15 tumor registries meeting the requirements were selected in Enshi Tujia and Miao Autonomous Prefecture. The incidence and death data of gastric cancer were collected, and the incidence and death rates were analyzed by gender and age. The normalized incidence rate and Hp positive rate of enshi city, Lichuan city and six counties including Jianshi, Badong, Xuan 'en, Xianfeng, Laifeng and Hefeng were compared. Spearman correlation analysis was used to analyze the correlation between standard incidence rate and Hp positive rate of gastric cancer in each district of Tujia and Miao Autonomous Prefecture of Enshi Prefecture. Results Both male and female had an upward trend. The average rate of standard incidence of gastric cancer in male and female was 4.07% and 4.15%, respectively, and there was no significant difference in the trend of standard incidence rate in different genders (P>0.05). The gross death rates and standardized death were decreased in both male and female. The average decreasing rate of standardized death rate of gastric cancer in males and females was -3.91% and -4.12%, respectively, and there was no significant difference in the trend of standardized death rate in different genders (P>0.05). Overall, the incidence rate in age group 50-80 from 2016 to 2020 was significantly higher than that from 2011 to 2015 (P<0.05). The mortality rate in the 60-80 age group from 2016 to 2020 was significantly lower than that from 2011 to 2015 (P<0.05). The trend of morbidity and mortality in different age groups was consistent in the two periods. There was a positive correlation between the incidence standard rate of gastric cancer and Hp positive rate (r =0.473, P<0.05). Conclusion From 2011 to 2020, the incidence and mortality of gastric cancer in Enshi Tujia and Miao Autonomous Prefecture were both at a high level, with an upward trend and a downward trend. The positive rate of Hp and the new infection rate of Hp in the high incidence area of gastric cancer were higher than those in the low incidence area.
