Clinical features of fundus lesions of 74 patients with acquired immunodeficiency syndrome in Shenyang
10.3980/j.issn.1672-5123.2023.3.31
- VernacularTitle:沈阳市74例获得性免疫缺陷综合征患者眼底病变的临床特征分析
- Author:
Xin-Xin SUN
1
;
Bai-Qing SHI
1
;
Chang-Lin SUN
1
Author Information
1. Department of Ophthalmology,Central Hospital of Liaoning Electric Power Supply Co., Ltd., Shenyang 110005, Liaoning Province, China
- Publication Type:Journal Article
- Keywords:
acquired immunodeficiency syndrome;
fundus lesions;
CD4+T cell;
cytomegalovirus;
risk factor
- From:
International Eye Science
2023;23(3):508-511
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the clinical features and factors of fundus lesions in patients with acquired immunodeficiency syndrome(AIDS)in Shenyang and the relationship between fundus lesions and CD4+T cell count.METHODS: Retrospective case study. A total of 74 cases with AIDS who were treated in the Central Hospital of Liaoning Electric Power Supply Co., Ltd., from January 2021 to December 2021 were selected. The fundus manifestation and CD4+T cell count of the patients were analyzed.RESULTS: The total detection rate of fundus lesions in AIDS patients was 58%. CD4+T cell count in the patients with fundus lesions was significantly lower than that in the patients with normal fundus [29(6, 55)/μL vs. 76(35, 103)/μL, P<0.01]. The rate of fundus lesions was the highest in the patients with CD4+T cell count ≤ 50/μL(74%). Logistic regression analysis showed that as the CD4+T cell count increased, the incidence of fundus lesions decreased(OR=0.977, 95%CI 0.964～0.991, P<0.01).CONCLUSION: Fundus lesions in AIDS patients related to CD4+T cell count. Decreasing CD4+T cell count was a risk factor of fundus lesions for AIDS patients. Routine fundus examination is important for the early diagnosis of fundus lesions in AIDS patients.
