Prevalence and risk factors of dry eye patients with corneal epithelial defects: A hospital-based retrospective study
10.3980/j.issn.1672-5123.2023.3.02
- VernacularTitle:干眼角膜上皮损伤患者患病率和危险因素的回顾性研究
- Author:
Yi-Ning GUO
1
;
Xiao-Dan JIANG
1
;
Yin-Hao WANG
1
;
Yue-Xin WANG
1
;
Hao YUAN
1
;
Xue-Min LI
1
Author Information
1. Department of Ophthalmology, Peking University Third Hospital, Beijing 100191, China; Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Beijing 100191, China
- Publication Type:Journal Article
- Keywords:
comorbidity;
corneal epithelial defects;
dry eye;
prevalence;
risk factor
- From:
International Eye Science
2023;23(3):356-362
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To analyze the characteristics and correlated risk factors of dry eye patients with corneal epithelial defects.METHODS: Outpatient medical records of dry eye patients with corneal epithelial defects at Peking University Third Hospital from July 2018 to June 2019 were retrospectively analyzed. The patients' data including sex, age, visit date, presence of comorbidities, and meteorological indicators at the same period were statistically analyzed.RESULTS: A total of 291 dry eye patients with corneal epithelial defects, of whom 75.3% were female, were retrospectively analyzed. Young patients aged 21-30 made up the most(26.5%), while the proportion of teenagers(<18 years, 5.8%)and the elderly(≥61 years, 17.2%)was low. However, as the largest proportion of this population, young and middle-aged patients tend to experience fewer visits(5.4±12.4). Spring and winter were the main seasons of complaints. The meteorological indicators at the same period including fine-particulate matter with a median aerometric diameter of less than 10μm(PM10), sulfur dioxide(SO2), nitrogen dioxide(NO2), and reduced average relative humidity were found significantly correlated with dry eye corneal epithelial defects(P<0.05). Conjunctivitis, cataracts, blurred vision, and trichiasis ranked the top four comorbidities.CONCLUSION: Dry eye corneal epithelial defects of young and female population cannot be ignored. PM10, SO2, NO2, and reduced humidity are found significantly correlated with dry eye corneal epithelial defects. For dry eye patients with conjunctivitis, cataracts, blurred vision, and trichiasis, more attention should be paid to their corneal conditions.
