Cancer and chemotherapy in pediatric COVID-19: A case series
https://doi.org/10.56964/pidspj20222302004
- Author:
Meg Tuazon
1
;
Mary Crist Delos Santos-Jamora
1
;
Sabrina Florendo-Villanueva
1
;
Rainelda Panlilio-Runez
1
Author Information
1. Baguio General Hospital and Medical Center
- Publication Type:Other Types
- MeSH:
COVID-19;
Drug Therapy;
Neoplasms;
Child
- From:
Pediatric Infectious Disease Society of the Philippines Journal
2022;23(2):19-30
- CountryPhilippines
- Language:English
-
Abstract:
Objectives:This case series aims to present three cases of pediatric cancer – two acute leukemia and one solid tumor with active COVID-19 infection who underwent chemotherapy
Methodology:Three cases of pediatric cancer who tested positive for SARS-CoV2 are presented. All proceeded with scheduled chemotherapy despite active COVID-19 infection. Two had no post-chemotherapy complications, while one had febrile neutropenia and hospital-acquired pneumonia.
Results:In this case series, COVID-19 infection in pediatric patients with cancer does not appear to be more severe compared with the general population. The severity of signs and symptoms can be attributed to a lower Cycle Threshold (CT) value and a co-infection. COVID-19 infection did not change the course and post-chemotherapy complications in all cases.
Conclusion:Patient demographics, comorbidities and type of malignancy played an essential role in the pre- and post-chemotherapy outcome. Individual patient factors including CT values, comorbidities, co-infections, COVID19 disease severity classification, and blood count picture are also instrumental in the management and outcome of these cases. Pediatric cancer treatment should be a priority during active COVID-19 infection.
- Full text:005_PIDSP-vol-23-no-2_TUAZON_3CS-layout-rev-1.pdf
