Application of Benadrly in Test of Drug-induced Electroencephalography of Epilepsy
- VernacularTitle:苯海拉明在药物诱发痫样脑电图试验中的应用
- Author:
Meng HU
;
Xinyou LIU
;
Xiaohui FU
;
Min HUANG
;
ZHEN LI
;
Zhongyin ZHANG
- Publication Type:Journal Article
- Keywords:
benadrly, drug-induced test, eilepsy, electroencephalography
- From:
Chinese Journal of Rehabilitation Theory and Practice
2010;16(6):587-588
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the test of drug-induced electroencephalography(EEG) and epilepsy.Methods324 patients with epilepsy were randomly divided into 2 groups, the benadrly group(n=162) and chloral hydrate group(n=162) as control. EEG was examined by evoking during sleep to observe epileptiform discharge and which stage of non-rapid eye movements (NREM) epileptiform discharge occurred more frequently.ResultsThe epileptiform discharge was 31.61% in benadrly group, and 18.52% in chloral hydrate group. There was significant difference between the two groups (P<0.01). The detection rate of epileptiform discharge at the stage I～II of NREM was significantly higher in benadrly group (83.7%) than in chloral hydrate group(63.3%)(P<0.05), which suggested that epileptiform discharge frequently occurred at the stage I～II of NREM.ConclusionBenadrly is superior to chloral hydrate in the test of drug-induced EEG of epilepsy.
