The effect of timing of oocyte denudation from oocyte retrieval in the total fertilization failure among in vitro fertilization - Intracytoplasmic sperm injection cycles.
- Author:
Gladys Anne M. BERMIO
1
;
Ma. Asuncion A. FERNANDEZ
2
;
Virgilio M. NOVERO
3
Author Information
- Publication Type:Journal Article
- Keywords: Oocyte denudation; Total fertilization failure (TFF); In-vitro fertilization intracytoplasmic injection
- From: Philippine Journal of Reproductive Endocrinology and Infertility 2022;19(1):13-22
- CountryPhilippines
- Language:English
-
Abstract:
Objective: This study aimed to evaluate the effect of oocyte incubation after retrieval in TFF among IVF-ICSI and identify factors affecting total fertilization failure (TFF).
Methods: This is a retrospective cohort study, involving 995 IVF cycles using the antagonist protocol that were clustered into three timings of oocyte denudation from retrieval : Group 1: <1 hour, Group 2: ?1 hour to <2hours and Group 3: ?2hours. Other variables considered were etiology of infertility, female age, days of stimulation and total number of oocytes retrieved.
Results: Overall TFF was 4.5%. TFF among groups were 4.8%, 5.8% and 3.2%, respectively. Multiple logistic regression analysis showed that oocyte incubation prior to denudation for ? 2 hours tend to decrease TFF incidence. Among factors studied, male factor infertility and a low number of oocytes adversely affect TFF.
Conclusion: Timing of incubation of oocyte did not significantly affect the occurrence of TFF. Among factors studied, male factor infertility and a low number of oocytes adversely affect TFF.
- Full text:-the-effect-of-timing-of-oocyte-denudation-from-oocyte-retrieval-in-the-total-fertilization-failure-among-in-vitro-fertilization-–-intracytoplasmic-sperm-injection-cycles.pdf
