Association of epidemiological characteristics and dietary patterns with risk of type 2 diabetic nephropathy
10.3969/j.issn.1006-2483.2023.01.030
- VernacularTitle:2型糖尿病肾病流行病学特征及膳食模式与患病风险关联性
- Author:
Ting QI
1
;
Xiao-tie TANG
1
;
Wei-yan SUN
1
Author Information
1. Department of Nephrology , Wuhan Puren Hospital , Wuhan , Hubei 430081 , China
- Publication Type:Journal Article
- Keywords:
Type 2 diabetic nephropathy;
Epidemiological characteristics;
Dietary pattern;
Risk of disease;
Correlation
- From:
Journal of Public Health and Preventive Medicine
2023;34(1):124-126
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the prevalence of diabetic nephropathy (DN) and the relationship between dietary pattern and risk. Methods From August 2018 to May 2021, 655 T2DM patients in Wuhan Puren Hospital, including 338 males and 317 females, were divided into T2DM group (n=368 cases) and DN group (n=287 cases) according to whether patients had DN. The uniformly trained staff of our hospital used the simplified version of food intake frequency questionnaire designed for diabetes to investigate the reasonable dietary intake of patients in nearly one year. Clinical data of patients in the two groups were collected and the intake of protein, fat, carbohydrate and dietary fiber in the two groups was statistically analyzed. Logistics regression was used to analyze the formula independent risk factors of DN in T2DM, and Pearson correlation analysis was performed on the incidence of diabetic nephropathy and dietary pattern. Results Among of 655 T2DM patients, there were 287 (43.82%) patients with DN, including 149 males and 138 females. The average age, duration of diabetes, smoking in DN group were significantly higher than those in T2DM group (P<0.05). There was no significant difference in sex ratio between the two groups (P>0.05). Energy, protein intake, carbohydrate and fat intake in DN group were significantly higher than those in T2DM group (P<0.05). Multivariate logistic regression analysis showed that protein, carbohydrate and fat intake were independent risk factors for DEVELOPING DN in T2DM patients (P<0.05). According to Pearson correlation analysis, the risk of developing DN in T2DM patients was positively correlated with protein and fat intake (r=0.449 , 0.517, P<0.05). Conclusion PATIENTS with T2DM have a higher risk of DEVELOPING DN, which is closely related to dietary intake. Reasonable allocation of dietary intake can reduce the risk of developing DN.
