Current status and development trend of coagulation factor Ⅷ activity
10.3760/cma.j.cn114452-20220126-00043
- VernacularTitle:凝血因子Ⅷ活性检测现状及发展趋势
- Author:
Yu LIU
1
;
Guanqun XU
;
Jing DAI
;
Xuefeng WANG
Author Information
1. 上海交通大学医学院附属瑞金医院检验科，上海 200025
- Keywords:
Factor Ⅷ;
Coagulation factor Ⅷ activity;
One-stage assay;
Chromogenic substrate assay;
Influencing factors
- From:
Chinese Journal of Laboratory Medicine
2022;45(10):1010-1016
- CountryChina
- Language:Chinese
-
Abstract:
The detection of coagulation factor Ⅷ activity plays an important role in the diagnosis, typing, efficacy monitoring and detection of inhibitor titer in hemophilia A, acquired hemophilia A and von Willebrand disease. However, due to the diversity of detecting systems, the difference of reagent composition, the existence of interfering substances and other influence factors, the detection of coagulation factor Ⅷ activity in the laboratories in China still needs to be improved.
