The present research and progress of angiopoietin in diabetic retinopathy
10.3760/cma.j.cn511434-20210707-00364
- VernacularTitle:血管生成素在糖尿病视网膜病变中的研究现状和进展
- Author:
Qingyan LIU
1
;
Yan SHAO
;
Xiaorong LI
Author Information
1. 天津医科大学眼科医院、眼视光学院、眼科研究所 国家眼耳鼻喉疾病临床医学研究中心天津市分中心 天津市视网膜功能与疾病重点实验室, 天津 300383
- Keywords:
Angiopoietins;
Diabetic retinopathy;
Receptor protein-tyrosine kinases;
Lipid metabolism;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2022;38(11):944-948
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes, and it is the main cause of vision loss in diabetic patients. Angiopoietin (Ang), a superfamily of secreted proteins, is a vascular growth factor that regulates the stability of vascular environment, participates in angiogenesis and repair, and lipid metabolism. It plays an important role in the development of DR and has become a new target for the treatment of diabetic retinopathy. With the in-depth study of Ang and the research and development of various drugs for Ang, it is expected to bring new ideas and strategies for the treatment of DR in the future.
