Research progress of white matter lesions in patients with obstructive sleep apnea hypopnea syndrome
10.3760/cma.j.cn113694-20211220-00902
- VernacularTitle:阻塞性睡眠呼吸暂停低通气综合征患者脑白质病变的研究进展
- Author:
Qiong WU
1
;
Lu JIN
;
Jing LI
;
Jialing LIU
;
Yongzhong LIN
Author Information
1. 大连医科大学附属第二医院神经内科，大连116000
- Keywords:
Sleep apnea, obstructive;
White matter lesions;
Pathogenesis;
Clinical manifestation;
Prognosis
- From:
Chinese Journal of Neurology
2022;55(8):914-920
- CountryChina
- Language:Chinese
-
Abstract:
White matter lesions in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) are common brain microstructural changes, the mechanism of which is still not clear, including decreased cerebral perfusion, oxidative stress, inflammatory damage, etc. At present, white matter lesions are mainly evaluated by magnetic resonance imaging. White matter lesions in patients with OSAHS are often manifested as cognitive dysfunction such as inattention, decreased executive ability and memory loss. Continuous positive airway pressure can relieve the white matter lesions and improve the cognitive function of some patients with OSAHS. Further study on the pathogenesis and early imaging characteristics of OSAHS white matter lesions is expected to provide targets and evidence for early intervention.
