The safety and prognosis of radical surgery in old patients of colorectal cancer

VernacularTitle:高龄结直肠癌患者行根治性手术的安全性及预后分析
Author: Meng WANG ¹ ; Yujuan JIANG ; Sicheng ZHOU ; Jianwei LIANG ; Zhaoxu ZHENG
Author Information

1. 国家癌症中心　国家肿瘤临床医学研究中心　中国医学科学院北京协和医学院肿瘤医院结直肠外科,北京　100021
Keywords: Colorectal neoplasms; Aged; Colorectal surgery; Safety; Prognosis
From: Chinese Journal of General Surgery 2022;37(6):425-429
CountryChina
Language:Chinese
Abstract: Objective:To evaluate the safety and feasibility of radical surgery and explore prognostic factors affecting cancer-specific survival (CSS) in elderly patients with colorectal cancer (CRC).Methods:From Jan 2010 to Dec 2020, a total of 372 elderly (aged over 80 years) CRC patients who underwent curative resection at the National Cancer Center were enrolled. Preoperative clinical features, perioperative outcomes and postoperative pathological characteristics were collected.Results:In the multivariable COX regression analysis, BMI ≥30 kg/m 2 ( HR:2.30, 95% CI: 1.27-4.17, P=0.006) and N1-N2 stage ( HR: 2.97,95% CI:1.48-5.97, P=0.002) correlated with worse CCS. Conclusions:The results of this study demonstrated that radical resection for CRC is safe and feasible for patients over 80 years of age. BMI and N stage were independent prognostic factors for elderly CRC patients after radical resection.