Repeated fracture-full moon face-perioral spotted pigmentation

VernacularTitle:反复骨折-满月脸-口周斑点样色素沉着
Author: Xiaohong LYU ¹ ; Shi CHEN ; Ou WANG ; Lin LU
Author Information

1. 中国医学科学院北京协和医学院北京协和医院内分泌科，国家卫生健康委员会内分泌重点实验室，北京　100730
Keywords: Carney complex; Osteochondromyxoma; Cushing syndrome
From: Chinese Journal of Endocrinology and Metabolism 2022;38(8):679-682
CountryChina
Language:Chinese
Abstract: Carney complex(CNC) is a rare disease in endocrinology, with osteochondromyxoma accounting for only 1% of it. This article details the diagnosis and treatment of a young female patient with recurrent fracture, full moon face and perioral spotted pigmentation. Combined with clinical manifestations, auxiliary examination and pathology, Carney complex with osteochondromyxoma was diagnosed. Multiple bone deformities in this case should be differentiated from McCune-Albright syndrome and ectopic ACTH secreting tumor with multiple bone metastases. The report of this case is helpful to improve the understanding of osteochondromyxoma in endocrinology, radiology, orthopedics and other disciplines, so as to avoid missed diagnosis and misdiagnosis.