Intraoperative radiotherapy in borderline resectable pancreatic carcinoma
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn113884-20220429-00197
   		
        
        	
        		- VernacularTitle:术中放疗在交界可切除胰腺癌中的应用
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yirui ZHAI
			        		
			        		
			        		
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			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院放疗科,北京 100021
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Pancreatic neoplasms;
			        		
			        		
			        		
				        		Pancreatectomy;
			        		
			        		
			        		
				        		Intraoperative radiotherapy
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Hepatobiliary Surgery
	            		
	            		 2022;28(8):572-575
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	The adjacency or invasion to great vessels such as superior mesenteric artery/vein and celiac axis increase the difficulties to achieve R 0 resection and evoked high local recurrence for patients with borderline resectable pancreatic cancer. Intraoperative radiation therapy refers to a single high-dose irradiation during the surgery, which achieved the purpose of precise target treatment and protected normal tissues. In borderline resectable pancreatic cancer, preoperative radiotherapy and chemotherapy combined with surgery and intraoperative radiotherapy has a better effect, and compared with surgery alone, the addition of intraoperative radiotherapy does not increase the risk of serious postoperative complications. Here, we summarized the application of intraoperative radiation therapy in borderline resectable pancreatic carcinoma.