Features of iris and fundus fluorescein angiography in diabetic iridopathy
10.3760/cma.j.cn115989-20210218-00115
- VernacularTitle:糖尿病虹膜病变的荧光素虹膜血管造影和荧光素眼底血管造影特征分析
- Author:
Shiqing LI
1
;
Zhili WANG
;
Xiao CHEN
;
Xiaohua LI
Author Information
1. 河南省人民医院眼科 河南省立眼科医院 河南省眼科研究所 郑州大学人民医院，郑州 450003
- Keywords:
Iris diseases/diagnosis;
Diabetic rubeosis iridis;
Diabetic retinopathy;
Fluorescein angiography, iris;
Fluorescein angiography, fundus
- From:
Chinese Journal of Experimental Ophthalmology
2022;40(9):847-851
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the imaging features of iris fluorescein angiography (IFA) combined with fluorescein fundus angiography (FFA) in diabetic iridopathy.Methods:A cross-sectional study was conducted.Sixty-five eyes of 44 patients with proliferative diabetic retinopathy (PDR) combined with diabetic iridopathy (DI) were enrolled in Henan Eye Hospital from May 2013 to May 2020.Patients were divided into non-proliferative diabetic iridopathy (NPDI) group and rubeosis iridis group according to the imaging results.Ophthalmic examinations including visual acuity, intraocular pressure, slit lamp miacroscopy, IFA and FFA were carried out in all patients.IFA was used to detect the iris imaging characteristics and the regression time of fluorescein in anterior chamber, and FFA was used to observe the retinal image characteristics and the incidence of optic disc neovascularization.To avoid the statistical error of recording the IFA examination time of the contralateral eye, only the relevant data of the affected eyes were analyzed.This study adhered to the Declaration of Helsinki.The study protocol was approved by the Ethics Committee of Henan Eye Hospital (No.HNEECKY-2020[06]). Written informed consent was obatined from all patients before any medical examination.Results:Among the patients, 30 cases (50 eyes) were with NPDI and 14 cases (15 eyes) were with rubeosis iridis.The fluorescein regression time in anterior chamber of NPDI group was (3.37±0.11) minutes, which was significantly shorter than (6.02±0.29) minutes of rubeosis iridis group ( t=8.541, P<0.001). Strong fluorescence of retinal neovascularization was observed in both groups.The incidence of optic disc neovascularization in NPDI group was 20% (6/30), which was significantly lower than 50% (7/14) in rubeosis iridis group ( P=0.04). Conclusions:Diabetic rubeosis iridis can be diagnosed by the imaging features of IFA and the fluorescein regression time in anterior chamber.PDR combined with optic disc neovascularization should be evaluated by FFA combined with IFA.
