Research status of molecularly imprinted hydrogel drug-loaded contact lenses
10.3760/cma.j.cn115989-20190430-00204
- VernacularTitle:分子印迹水凝胶载药角膜接触镜的研究现状
- Author:
Jiangning XU
1
;
Tong ZHOU
Author Information
1. 重庆医药高等专科学校，重庆 401331
- Keywords:
Contact lenses;
Molecular imprinting technology;
Hydrogel;
Drug release
- From:
Chinese Journal of Experimental Ophthalmology
2022;40(7):685-689
- CountryChina
- Language:Chinese
-
Abstract:
Traditional ophthalmic pharmaceutical preparations are mostly eye drops or eye ointments, which have the disadvantages of low efficiency and poor patient compliance in application.Drug-loaded contact lenses can overcome these shortcomings and have attracted much attention.Improving drug loading capacity and enhancing sustained-release performance of drug-loaded contact lenses are the main focus of research and development.In recent years, drug-loaded contact lenses made of molecularly imprinted hydrogel can significantly improve drug loading capacity and sustained-release performance, and have been widely studied.The application status of molecularly imprinted hydrogel drug-loaded contact lenses in the delivery of ophthalmic drugs, as well as the effects of various factors on drug loading capacity and sustained-release performance were reviewed in this article.
