Research progress of neutrophil extracellular traps in rheumatic diseases
10.3760/cma.j.cn101070-20210407-00403
- VernacularTitle:中性粒细胞外陷阱在风湿性疾病中的研究进展
- Author:
Yuying FANG
1
;
Haiguo YU
Author Information
1. 南京市儿童医院/南京医科大学附属儿童医院风湿免疫科，南京 210008
- Keywords:
Neutrophils;
Neutrophil extracellular traps;
Rheumatic diseases
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(18):1438-1440
- CountryChina
- Language:Chinese
-
Abstract:
Rheumatic diseases are inflammatory diseases characterized by severe immune dysregulation, which can affect tissues and joints.Neutrophils are the key factor contributing to immune disorders, and they play an important role in rheumatic diseases.Neutrophil extracellular traps (NETs) are network structures released by neutrophil granulocytes when stimulated.As a novel immune defense mechanism, NETs have attracted wide attention.In this paper, the formation, function and role of NETs in rheumatic diseases and other diseases were reviewed.
