Research progress on signaling pathway of Traditional Chinese Medicine inhibiting leukemia cell proliferation and inducing apoptosis
10.3760/cma.j.cn115398-20210705-00040
- VernacularTitle:中药抑制白血病细胞增殖及诱导细胞凋亡信号通路研究进展
- Author:
Xiaolin MA
1
;
Changgui LI
;
Kai WANG
;
Xiaojing LI
;
Yongming ZHOU
Author Information
1. 上海中医药大学2019级硕士研究生，上海 201203
- Keywords:
Leukemia;
Traditional Chinese Medicine (TCM);
Apoptosis;
Signaling pathways;
Review
- From:
International Journal of Traditional Chinese Medicine
2022;44(6):712-715
- CountryChina
- Language:Chinese
-
Abstract:
Traditional Chinese Medicine (TCM) can inhibit the proliferation of leukemia cells and induce apoptosis. The signaling pathways involved mainly include PI3K/Akt pathway, MAPK signaling pathway, JAK-STAT pathway, Wnt pathway and mitochondrial pathway. Among them, the mitochondrial apoptotic pathway is affected by many key apoptotic pathways, which plays a terminal role in promoting apoptosis. At present, there is a great need for the systematic and comprehensive research on various signaling pathways and intermolecular interactions.
