Research progress on the background of inflammation, immunity and cholesterol metabolism in colorectal cancer
10.3760/cma.j.cn371439-20220715-00126
- VernacularTitle:结直肠癌炎症、免疫及胆固醇代谢背景研究进展
- Author:
Chi YANG
1
;
Changjiang LUO
Author Information
1. 兰州大学第二医院普通外科,兰州 730000
- Keywords:
Colorectal neoplasms;
Therapy;
Molecular mechanisms
- From:
Journal of International Oncology
2022;49(10):630-634
- CountryChina
- Language:Chinese
-
Abstract:
At present, many treatment options for colorectal cancer, including chemotherapy, targeted therapy and immunotherapy, have poor efficacy due to resistance variation and patient individualization. It is urgent to find new precise and effective treatment measures at this stage. Studies have shown that the pathogenesis and progression of colorectal cancer involve multiple processes such as inflammation, immunity, and cholesterol metabolism, and there are many types of potential interactive reactions. Clarifying the regulatory mechanism of various factors is helpful to provide new ideas for colorectal cancer treatment.