Research progress of FOXO1 in oral squamous cell carcinoma
10.3760/cma.j.cn371439-20220414-00121
- VernacularTitle:FOXO1在口腔鳞状细胞癌中的研究进展
- Author:
Fan YANG
1
;
Xiaoyan GUAN
;
Jianguo LIU
;
Linlin XIAO
;
Chaoyi YUE
;
Qian LONG
;
Chengcheng LIAO
Author Information
1. 遵义医科大学附属口腔医院正畸科二组，遵义 563000
- Keywords:
Forkhead box protein O 1;
Oral neoplasms
- From:
Journal of International Oncology
2022;49(10):612-614
- CountryChina
- Language:Chinese
-
Abstract:
Forkhead box protein O1 (FOXO1) has been extensively studied as a tumor suppressor. In oral squamous cell carcinoma, studies have demonstrated that FOXO1 can inhibit tumor cell oxidative stress, stemness and epithelial-mesenchymal transition, and promote tumor cell autophagy and apoptosis. FOXO1 may serve as a potential target for the treatment of oral squamous cell carcinoma.
