Progress of plasma soluble CD14 subtype in neonatal septicemia
10.3760/cma.j.issn.1673-4408.2022.08.011
- VernacularTitle:血浆可溶性CD14亚型在新生儿败血症中的研究进展
- Author:
Jun WAN
1
;
Xiaoying LU
;
Xiaomei ZHANG
Author Information
1. 内蒙古医科大学，呼和浩特 010020
- Keywords:
Neonatal septicemia;
Soluble CD14 subtype
- From:
International Journal of Pediatrics
2022;49(8):553-557
- CountryChina
- Language:Chinese
-
Abstract:
Neonatal sepsis is a common infectious disease in the neonatal period, and its morbidity and mortality are increasing year by year.Its etiology and pathogenesis have not been fully elucidated.In recent years, studies have confirmed that plasma soluble CD14 subtype(sCD14-ST)plays a certain role in the pathogenesis of neonatal sepsis, and has a certain value in its diagnosis and prevention.The study found that sCD14-ST could be used as an indicator for early auxiliary diagnosis of neonatal sepsis, and the expression of sCD14-ST was positively correlated with the degree of neonatal sepsis.Early detection of sCD14-ST can predict neonatal sepsis.This article reviews the research on sCD14-ST and its application in neonatal sepsis.
