Progress on the relationship between vitamin D and neonatal bronchopulmonary dysplasia
10.3760/cma.j.issn.1673-4408.2022.08.005
- VernacularTitle:维生素D与新生儿支气管肺发育不良关系的研究进展
- Author:
Jian KANG
1
;
Jianhua FU
Author Information
1. 中国医科大学附属盛京医院儿内科，沈阳 110004
- Keywords:
Bronchopulmonary dysplasia;
Preterm infant;
Vitamin D;
Vitamin D supplement;
Vitamin D deficiency
- From:
International Journal of Pediatrics
2022;49(8):524-528
- CountryChina
- Language:Chinese
-
Abstract:
Bronchopulmonary dysplasia is one of the most common complications of preterm infants.The main pathological feature is dysplasia of the alveoli and pulmonary microvessels.Vitamin D is a steroid hormone.By binding to vitamin D receptors, it can protect the barrier function of alveolar epithelium, promote pulmonary vascularization, inhibit pulmonary fibrosis, regulate immune function, and repair damaged lung epithelial cells.It is beneficial to lung development and the improvement of lung function in preterm infants.Therefore, monitoring the level of vitamin D in the perinatal period and supplementing with appropriate doses is expected to be one of the ways to reduce the occurrence of moderate and severe bronchopulmonary dysplasia and improve the lung development of preterm infants.
