Rapid health technology assessment of Xuesaitong injection in the treatment of stroke
- VernacularTitle:血塞通注射液治疗中风的快速卫生技术评估
- Author:
Bihua ZHANG
1
;
Hui SHAO
2
;
Aijun YE
1
;
Liping YANG
1
Author Information
1. Dept. of Pharmacy，Beijing Hospital/National Center of Gerontology/Institute of Geriatric Medicine，Chinese Academy of Medical Sciences/Beijing Key Laboratory of Assessment of Clinical Drugs Risk and Individual Application（Beijing Hospital），Beijing 100730，China
2. Dept of Audit，Beijing Xuanwu Hospital of Traditional Chinese Medicine，Beijing 100050，China
- Publication Type:Journal Article
- Keywords:
Xuesaitong injection;
stroke;
pharmacoeconomics;
rapid health technology assessment
- From:
China Pharmacy
2023;34(1):97-101
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the efficacy， safety and economical efficiency of Xuesaitong injection in the treatment of stroke by rapid health technology assessment，so as to provide evidence for clinical rational drug use. METHODS Retrieved from Wanfang database， CBM， CNKI，PubMed，Cochrane Library，Embase， INAHTA and HTAI databases or organization websites， health technology assessment （HTA） reports， meta-analysis/systematic reviews and pharmacoeconomic studies related to Xuesaitong injection in the treatment of stroke were summarized and analyzed. RESULTS A total of 29 pieces of literature were included. Among them， 14 studies were conducted on meta-analysis/systematic reviews，15 studies were conducted on pharmacoeconomics， HTA was not obtained. The results of meta-analysis/systematic reviews showed that Xuesaitong injection had certain advantages for stroke in improving the total effective rate， clinical symptoms and related scale scores compared with blank control group and some drug control groups. Safety studies had shown that the adverse reactions of Xuesaitong injection were mainly allergic-like reactions. The results of pharmacoeconomic evaluation are quite different， which may also be related to the long time span among various studies and the adjustment of some drug prices. CONCLUSIONS Xuesaitong injection in the treatment of stroke is helpful to improve the clinical efficacy and evaluation indexes， but there are some serious adverse reactions， and it is not economically superior to some chemical drugs.
