A review of lignans from genus Kadsura and their spectrum characteristics
10.1016/j.chmed.2021.01.005
- Author:
Liu ZHANG
1
;
Yan-zhe JIA
1
;
Bin LI
1
;
Cai-yun PENG
1
;
Yu-pei YANG
1
;
Wei WANG
1
;
Chang-xiao LIU
2
Author Information
1. TCM and Ethnomedicine Innovation & Development International Laboratory, School of Pharmacy, Hunan University of Chinese Medicine
2. State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research
- Publication Type:Journal Article
- Keywords:
Kadsura;
lignans;
pharmacodynamics;
Q-marker;
structure classifications
- From:
Chinese Herbal Medicines
2021;13(2):157-166
- CountryChina
- Language:Chinese
-
Abstract:
Kadsura belongs to the Schisandroideae subfamily of Magnoliaceae. Plants from genus Kadsura are widely distributed in the South and Southwest of China. The plants of the genus are widely used as folk medicine for a long time in history, with the functions of relieving pain, promoting ‘qi’ circulation, activating blood resolve stasis, and applications in the treatment of rheumatoid arthritis and gastroenteric disorders. Lignans are the primary characteristic constituents with various biological activities of plants from genus Kadsura. This paper summarized 81 lignans isolated from the plants of genus Kadsura over the past eight years (from 2014 to 2021), which belong to five types: dibenzocyclooctadienes, spirobenzofuranoid dibenzocyclooctadienes, aryltetralins, diarylbutanes and tetrahydrofurans. Each type of these lignans possess typical characteristics in proton magnetic resonance (
