Prevalence and risk factors of silicosis complicated with chronic obstructive pulmonary disease.
10.3760/cma.j.cn121094-20211231-00644
- VernacularTitle:矽肺合并慢性阻塞性肺疾病患病率和危险因素分析
- Author:
Qian ZHAO
1
;
Ya Li FAN
2
;
Rui Min MA
2
;
Yuan Ying WANG
2
;
Qian ZHANG
2
;
Qiao YE
2
Author Information
1. Department of Occupational Medicine and Toxicology, Clinical Center for Interstitial Lung Diseases, Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China National Center For Occupational Safety and Health, Beijing 102300, China.
2. Department of Occupational Medicine and Toxicology, Clinical Center for Interstitial Lung Diseases, Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease;
Risk factor;
Silicosis;
Smoking
- MeSH:
Cross-Sectional Studies;
Female;
Humans;
Male;
Prevalence;
Pulmonary Disease, Chronic Obstructive/epidemiology*;
Retrospective Studies;
Risk Factors;
Silicosis/epidemiology*
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2022;40(8):602-606
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the prevalence, clinical characteristics and risk factors of chronic obstructive pulmonary disease (COPD) in silicosis patients. Methods: In May 2021, a cross-sectional study was used to retrospectively include 329 silicosis patients first diagnosed in Beijing Chaoyang Hospital from January 1, 2007 to December 31, 2020. The demographic data, occupational history, chest imaging, pulmonary function and blood routine indicators of silicosis patients with COPD were analyzed, and the risk factors of silicosis with COPD were analyzed by multiple logistic regression. Results: There were 128 patients with silicosis complicated with COPD, and the overall prevalence rate was 38.9% (128/329) . Among them, 73.4% (94/128) were male and 33.6% (43/128) were heavy smokers; 33.6% (43/128) of patients were classified as gold 1, 37.5% (48/128) as gold 2, 25.0% (32/128) as gold 3, and 3.9% (5/128) as gold 4. Diagnostic age (OR=1.04, 95%CI=1.02~1.06, P<0.001) , cumulative smoking (OR=1.03, 95%CI=1.01~1.05, P=0.008) and silicosis stage III (OR=7.06, 95% CI=4.00-12.46, P<0.001) were risk factors for silicosis complicated with COPD. Conclusion: Diagnostic age, cumulative smoking volume and third stage of silicosis are the risk factors of silicosis patients with different degrees of COPD, which should be paid attention to in clinical treatment.
