Transmission characteristics and risk factors of household COVID-19 clusters caused by 2019-nCoV Omicron variant in Tianjin.
10.3760/cma.j.cn112338-20220425-00340
- VernacularTitle:新型冠状病毒Omicron变异株引发天津市家庭聚集性疫情的传播特征及影响因素
- Author:
Guo Ping ZHANG
1
;
Cheng SU
1
;
Jie YANG
1
;
Fang Zhe YAN
1
;
Wei Shen WU
1
;
Jian Yun BAI
1
;
Zhao Fei WEI
1
;
Ying ZHANG
1
Author Information
1. Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China.
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
COVID-19/epidemiology*;
COVID-19 Vaccines;
Child;
Humans;
Influenza, Human/epidemiology*;
Middle Aged;
Pharyngitis;
Risk Factors;
SARS-CoV-2;
Young Adult
- From:
Chinese Journal of Epidemiology
2022;43(9):1370-1375
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To understand the transmission characteristics and risk factors of household COVID-19 clusters caused by 2019-nCoV Omicron variant in Tianjin and provide evidence for COVID-19 prevention and control. Methods: Field epidemiological method was used to investigate the epidemiological characteristics of COVID-19 cases, and descriptive analysis was used to describe the epidemiological information. Results: A total of 430 cases were reported in this epidemic in Tianjin, in which 409 cases were included in this study. Among these cases, 70.90% (290/409) occurred in families. The family secondary attack rate was 33.64% The family secondary attack rate in age group 12-17 years (13.79%) was significantly lower than that in age group 18-49 years (36.48%), the OR was 0.378 (95%CI: 0.170-0.840). The logistic regression analysis showed that compared with centralized quarantine, the OR of the index cases found in closed-off/controlled areas and in home quarantine were 2.951 (95%CI:1.322-6.586) and 2.287 (95%CI:1.164-4.495), respectively, compared with the cases without sore throat, the OR of the index cases with sore throat was 3.003 (95%CI: 1.576-5.720), and compared with cases in families without completed COVID-19 vaccinations in all members, the OR of the cases in families with completed COVID-19 vaccinations in all members was 0.268 (95%CI: 0.132-0.552). Conclusions: The risk of household transmission of infection with Omicron variant was high. Detecting the index case in closed-off/controlled areas or in home quarantine and sore throat in index cases were the risk factors of the household transmission, completed COVID-19 vaccination was the protective factor.
