Application progress of liquid chromatography tandem mass spectrometry in precision medicine.
10.3760/cma.j.cn112150-20211207-01128
- VernacularTitle:液相色谱串联质谱技术在精准医疗中的应用进展
- Author:
Jing Yi JIN
1
;
Fu Rong QIU
1
;
Yu ZHANG
2
Author Information
1. Laboratory of Clinical Pharmacokinetics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
2. Department of Clinical Laboratory, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Chromatography, Liquid/methods*;
Tandem Mass Spectrometry/methods*;
Precision Medicine;
Reproducibility of Results
- From:
Chinese Journal of Preventive Medicine
2022;56(11):1675-1684
- CountryChina
- Language:Chinese
-
Abstract:
Liquid chromatography tandem mass spectrometry (LC-MS/MS) is an analytical method that combines high separation of liquid chromatography with high selectivity and sensitivity of mass spectrometry. In recent years, LC-MS/MS has been widely used in clinical practice, including screening of inherited disorders, determination of endogenous compounds and analysis of biomarkers. LC-MS/MS is of great value to the precision prevention, diagnosis and treatment of some diseases due to its accurate data. This article not only illustrates the advantages of LC-MS/MS in precision medicine, but also prospects the future trend of LC-MS/MS in clinical practice, which expects to promote the development of clinical LC-MS/MS in the prevention, diagnosis and treatment of diseases.
