In vitro evaluation of a newly produced resin-based endodontic sealer.
	    		
		   		
		   			
		   		
	    	
    	 
    	10.5395/rde.2016.41.3.189
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yoo Seok SONG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Yoorina CHOI
			        		
			        		;
		        		
		        		
		        		
			        		Myung Jin LIM
			        		
			        		;
		        		
		        		
		        		
			        		Mi Kyung YU
			        		
			        		;
		        		
		        		
		        		
			        		Chan Ui HONG
			        		
			        		;
		        		
		        		
		        		
			        		Kwang Won LEE
			        		
			        		;
		        		
		        		
		        		
			        		Kyung San MIN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Conservative Dentistry, School of Dentistry and Institute of Oral Bioscience, Chonbuk National University, Jeonju, Korea. endomin@gmail.com
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Original Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Biocompatibility;
			        		
			        		
			        		
				        		Microleakage;
			        		
			        		
			        		
				        		Physicochemical;
			        		
			        		
			        		
				        		Sealer
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Cell Survival;
				        		
			        		
				        		
					        		Dental Pulp Cavity;
				        		
			        		
				        		
					        		Gutta-Percha;
				        		
			        		
				        		
					        		Hydrogen-Ion Concentration;
				        		
			        		
				        		
					        		Immersion;
				        		
			        		
				        		
					        		In Vitro Techniques*;
				        		
			        		
				        		
					        		Methylene Blue;
				        		
			        		
				        		
					        		Solubility;
				        		
			        		
				        		
					        		Tooth
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:Restorative Dentistry & Endodontics
	            		
	            		 2016;41(3):189-195
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	OBJECTIVES: A variety of root canal sealers were recently launched to the market. This study evaluated physicochemical properties, biocompatibility, and sealing ability of a newly launched resin-based sealer (Dia-Proseal, Diadent) compared to the existing root canal sealers (AHplus, Dentsply DeTrey and ADseal, Metabiomed). MATERIALS AND METHODS: The physicochemical properties of the tested sealers including pH, solubility, dimensional change, and radiopacity were evaluated. Biocompatibility was measured using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. For microleakage test, single-rooted teeth were instrumented, and obturated with gutta-percha and one of the sealers (n = 10). After immersion in 1% methylene blue solution for 2 weeks, the specimens were split longitudinally. Then, the maximum length of staining was measured. Statistical analysis was performed by one-way analysis of variance followed by Tukey test (p = 0.05). RESULTS: Dia-Proseal showed the highest pH value among the tested sealers (p < 0.05). ADseal showed higher dimensional change compared to AHplus and Dia-Proseal (p < 0.05). The solubility values of AHplus and Dia-Proseal were similar, whereas ADseal had the lowest solubility value (p < 0.05). The flow values of sealer in increasing order were AHplus, DiaProseal, and ADseal (p < 0.05). The radiopacity of AHplus was higher than those of ADseal and Dia-Proseal (p < 0.05). The cell viability of the tested materials was statistically similar throughout the experimental period. There were no significant differences in microleakage values among the tested samples. CONCLUSIONS: The present study indicates that Dia-Proseal has acceptable physicochemical properties, biocompatibility, and sealing ability.