Jeju seaweeds suppress lipopolysaccharide-stimulated proinflammatory response in RAW 264.7 murine macrophages

Author: Eun-Jin YANG ¹ ; Ji-Young MOON ¹ ; Sang Suk KIM ¹ ; Nam Ho LEE ¹ ; Chang-Gu HYUN ¹ ; Eun-Jin YANG ² ; Ji-Young MOON ² ; Wook Jae LEE ² ; Sang Suk KIM ³ ; Kyong-Wol YANG ⁴ ; Chang-Gu HYUN ⁵
Author Information

1. Cosmetic Science Center, Department of Chemistry, Jeju National University
2. Jeju Technopark
3. Citrus Research Station, National Institute of Horticultural and Herbal Science, RDA
4. Jeju Love Co., Ltd.
5. LINC Agency, Jeju National University
Publication Type:Journal Article
Keywords: Interleukin-6; Nitric oxide; Proinflammatory mediators; Prostaglandin E; Seaweeds; Tumor necrosis factor-α
From:Asian Pacific Journal of Tropical Biomedicine 2014;4(7):529-537
CountryChina
Language:Chinese
Abstract: Objective: To investigate the anti-inflammatory effects of Jeju seaweeds on macrophage RAW 264.7 cells under lipopolysaccharide (LPS) stimulation. Methods: Ethyl acetate fractions were prepared from five different types of Jeju seaweeds, Dictyopteris divaricata (D. divaricata), Dictyopteris prolifera (D. prolifera), Prionitis cornea (P. cornea), Grateloupia lanceolata (G. lanceolata), and Grateloupia filicina (G. filicina). They were screened for inhibitory effects on proinflammatory mediators and cytokines such as nitric oxide (NO), prostaglandin E